产品货号:
Z12955
中文名称:
CD95/FAS抗体
英文名称:
Anti-CD95/FAS Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CD95/FAS Antibody |
指标别名 | ALPS1A;APO 1;Apo 1 antigen;APT1;CD95;FAS;FAS/CD95;FAS1;FASLG receptor;FASTM;TNFRSF6 |
克隆性 | Polyclonal |
检验物种 | mouse,rat |
应用范围 | WB,IHC,IHC-F |
基因名称 | FAS |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of rat Fas(87-109aa,YTDRKHYSDKCRRCAFCDEGHGL). |
实际分子量 | 50KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | FAS(also known as surface antigen APO1 or CD95) is a member of the tumour-necrosis receptor factor family of death receptors,can induce apoptosis or,conversely,can deliver growth stimulatory signals.It acts as an inducer of both neurite growth in vitro and accelerated recovery after nerve injury in vivo.Fas antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance.The FAS antigen shows structural homology with a number of cell surface receptors,including tumor necrosis factor(TNF) receptors and the low-affinity nerve growth factor receptor(NGFR) and is mapped to 10q24.1.And the FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis. |
Uniprot ID | Q63199 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | Fas(TNF receptor superfamily,member 6) |
蛋白名全称 | Tumor necrosis factor receptor superfamily member 6 |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Immunohistochemistry in frozen section (IHC-F) 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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